Juvenile Polyps: a large pediatric cohort

Background Juvenile polyps, classified as hamartomatous lesions with neoplastic potential, are the most common gastrointestinal polyp of childhood. Risk factors for neoplasia include germline DNA mutations, a family history of juvenile polyps, and multiple polyps (≥3 or ≥5). Only a few large pediatric series (>100patients) of patients with juvenile polyps have been reported, with limited data about repeat surveillance colonoscopy and the incidence of neoplasia. The primary aim of this study was to identify a large cohort of children with one or more juvenile polyps for descriptive analysis of patient demographics, polyp number, location, repeat co1onoscopy, and neoplasia.